Crosstalk between Maternal Life and Fetal Epigenome; A Review Article

Background: It is important to say that maternal lifestyle during gestation could affect embryonic development and health consequences. Objectives: Many endogenous and exogenous factors affect the epigenetics of the germ cells during their division and subsequently affect the embryogenesis. Methods: This systematic review outline various studies that link the different environmental factors and modification in the fetal epigenome. Conclusion: Aberrant fetal epigenome modification subsequently affects the healthy embryonic growth and their contribution to the phenotypic changes and chronic disease development later in life.